Polyarteritis Nodosa

Polyarteritis nodosa (PAN), a form of vasculitis, is a serious blood vessel disease in which small and medium‐sized arteries become swollen and damaged. This auto immune disease of unknown origin affects the arteries and blood vessels that carry oxygen and blood to the organs and tissues.

More adults than children are affected with polyarteritis nodosa; while the disease can strike people of any age, it usually first appears in people between the ages of 40 and 50.

Polyarteritis nodosa mimics many diseases and symptoms can vary widely. The disease may be acute with a fever and on‐going for a long time; milder but fatal within several months; or appear as a chronic, debilitating disease. The vessels of the kidneys, liver, heart, stomach, and intestines are most often affected. Treatment is focused on decreasing the inflammation of the arteries by suppressing the immune system.

Symptoms of Polyarteritis Nodosa

Specific symptoms vary depending on where the affected areas of the arteries are, how severe they are, how much of the blood circulation they affect and what the impact is on various organs.

The most common symptoms are:
  • Fatigue
  • Fever
  • Numbness, tingling or weakness of the hands and feet
  • Pain in the joints, especially the large ones
  • Skin rash with raised reddish‐purple patches and knobs that can be felt along affected arteries
  • Abdominal pain, sometimes with nausea, and vomiting
  • Blood in the urine
  • Swelling
  • Weakness
  • Weight loss



HOW TO PREPARE FOR YOUR APPOINTMENT

For general information or to schedule an appointment, call 212.305.4308. You may need a doctor's referral; please consult with your insurance provider prior to your appointment to ensure your visit will be covered under your policy.

Your appointment

  • To prepare for your appointment, make a list of all prescription and over-the-counter medications you take. Include the dosage and frequency with which you take them. Please bring the list with you to your appointment.
  • First-time office consultations typically require an hour long appointment.
  • Please arrive 15 minutes prior to your scheduled appointment for registration.
  • It is not necessary to fast for your first visit, unless you are instructed to do so by the doctor.
  • If you are not a current Columbia/NYP patient, please bring your outside medical records with you or ask your doctor to fax them to us at 212.342.6835.
  • A brief medication information form will need to be completed at each visit.
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