Wegener’s granulomatosis is a rare form of vasculitis. Vasculitis is an inflammation of the blood vessels that limits the flow of blood to important organs and tissues, causing potentially significant damage.

Although the disease can involve any organ system, Wegener's granulomatosis mainly affects the respiratory tract (sinuses, nose, trachea and lungs) and kidneys. It affects men and women equally but is more prevalent among middle‐aged people. Wegener’s granulomatosis is unusual in African Americans compared with Caucasians.

Symptoms of Wegener’s granulomatosis

Symptoms of Wegener’s granulomatosis are often not specific. They can begin slowly with fever, weight loss and muscle aches. They can also come on suddenly and progress quickly, leading to kidney failure. Eye problems develop in many people with Wegener's granulomatosis. The eye problems range from mild conjunctivitis to severe swelling of the eye.

Other symptoms include:
  • Frequent sinusitis
  • Fatigue and general malaise
  • Fever without obvious cause
  • Night sweats
  • Chronic ear infections
  • Nose bleeds
  • Loss of appetite and weight loss
  • Pain and sores around the opening of the nose
  • Chest pain
  • Cough, with or without blood
  • Blood in the urine
  • Joint pain
  • Shortness of breath
  • Wheezing


For general information or to schedule an appointment, call 212.305.4308. You may need a doctor's referral; please consult with your insurance provider prior to your appointment to ensure your visit will be covered under your policy.

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